Assessment of Chemical Composition by Raman Spectroscopy

The RDI service dedicated to the assessment of chemical composition by Raman spectroscopy offers the rapid, accurate and non-destructive analysis of solid and liquid materials. By examining inelastically scattered light, the method identifies the vibrational modes specific to the chemical structure of a substance, allowing material identification, molecular characterisation and compositional assessment.

The service is suitable for identifying unknown substances, detecting impurities and characterising polymers, pigments, pharmaceutical products and industrial materials, as well as for supporting failure cause analysis and quality control. In pharmaceutical applications, Raman spectroscopy can be used to identify polymorphic forms, verify the purity of raw materials and detect counterfeit products, including through transparent packaging. It also supports the real-time monitoring of reactions, by following intermediate species and process conditions without interrupting the technological flow.

The method is particularly valuable in the field of cultural heritage and art conservation, since it allows the non-invasive analysis of pigments, polymers and degradation products in works of art and artefacts. These investigations can contribute to assessing authenticity, documenting materials and selecting appropriate conservation strategies.

The potential beneficiaries include companies, laboratories, research institutions and public organisations active in fields such as electronics and semiconductors, the chemical and pharmaceutical industries, materials and the processing industry, environmental and forensic analyses, the food industry and agriculture, metallurgy, art and heritage conservation, cosmetics and related sectors.

Delivering the service requires specialised equipment and resources, including a Xantus 2 Raman spectrometer, instruments for grinding and sieving the samples, standards for calibration and method verification, vials for liquids, an internal spectral library and the auxiliary materials needed for sample preparation and analysis.